TARGETED DELIVERY OF OXALIPLATIN VIA FOLATE-DECORATED NIOSOMAL NANOPARTICLES POTENTIATES RESISTANCE REVERSION OF COLON CANCER CELLS

Targeted delivery of oxaliplatin via folate-decorated niosomal nanoparticles potentiates resistance reversion of colon cancer cells

Background: Colorectal cancer (CRC) is a prevalent type of cancer, ranking third in incidence and fourth in cancer-related deaths globally.The increase in mortality rates related to colorectal cancer among younger patients is a cause for concern.Chemotherapy is the primary approach for palliative care in colon cancer, but the development of drug re

read more


The elevated gradient of aversion: a new apparatus to study the rat behavior dimensions of anxiety, fear, and impulsivity

Few behavioral tests allow measuring several characteristics and most require training, complex analyses, and/or are time-consuming.We present an apparatus based on rat exploratory behavior.Composed of three different environments, it allows the assessment of more than one behavioral characteristic in a short 3-min session.Factorial analyses have d

read more

High Selectivity Single Wideband and Quad-Band HTS Filters Using Novel Quad-Mode Resonators With Self-Coupled Structure

This paper presents improved quad-mode resonators based on the open/short-end load of the center stub, which introduces the self-coupled structure.Compared with the traditional stub-loaded stepped impedance resonator (SLSIR), the proposed quad-mode resonators can significantly reduce the circuit size and further increase the design freedom.First of

read more